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What Is THC?

White pyramid on teal background with the words, 'Tetrahydrocannabinol, What Is THC?' placed in the middle.
Tetrahydrocannabinol (THC) is the most well-known psychoactive and psychotropic chemical compound found in cannabis plants. It's a naturally occurring compound that has been used medicinally and recreationally for centuries. In this Comprehensive Guide to THC, you will learn more about Tetrahydrocannabinol than the majority of all mankind.

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Table of Contents

What Is Tetrahydrocannabinol?

As mentioned earlier, Tetrahydrocannabinol (THC) is a chemical compound known as a cannabinoid and since it’s naturally-derived from a plant, it is a phytocannabinoid (phyto = from a plant).

THC is the main active compound of cannabis plants that is infamous for giving consumers a “high” sensation, but is now growing in popularity worldwide for its potential use in medicine, specifically, the medical marijuana industry.

THC is known to have psychoactive and psychotropic effects, meaning it can be mind-activating and state-of-mind altering, respectively, and can causes changes in perception, mood, and behavior.

There are many different types of THC like THC analogs and THC cannabinoid derivatives, this brings us to our next topic.

ALL Of The Different Types of THC

The topics I’ll cover in this section are vast, informative, and what I believe are very important pieces of information to know about THC.  The topics include:

  • A List Of All The Different Types of THC (with Acronyms)
  • THC Analogs
  • THC Derivatives
  • The Strongest Types of THC (listed in order from greatest to least)
  • How Different THC Molecules Get Their Numbers

 

To start this off, I want to give you the best resource I’ve found online. Seriously, I was awed at the amount of information I found here, Phytocannabinoids:  A Unified Critical Inventory. This white paper is the most in-depth analysis and breakdown of all the different cannabinoids I’ve ever found

I hope you enjoy it!

For now, let’s jump into the first topic from the list above.

A List Of All The Different Types Of THC (With Acronyms)

  1. 10-oxo-delta-6a-tetrahydrocannabinol, (OTHC)
  2. Delta-8-tetrahydrocannabinolic acid, (Δ8-THCA)
  3. Delta-8-tetrahydrocannabinol (d8THC, Δ8-THC)
  4. Delta-9-tetrahydrocannabinol (d9THC, Δ9-THC)
  5. Delta-9-tetrahydrocannabinol-C4 (THC-C4)
  6. Delta-9-tetrahydrocannabinolic acid A (Δ9-THCA, THCA-C5)
  7. Delta-9-tetrahydrocannabinolic acid B (Δ9-THCB, THCA-B)
  8. Delta-9-tetrahydrocannabiorolic acid, (Δ9-THCA-C1, THCA-C1)
  9. Delta-9-tetrahydrocannabinolic acid C4, (Δ9-THCA-C4, THCA-C4)
  10. Tetrahydrocannabinol(−)-cis-Δ (THC-C5)
  11. Delta-9-tetrahydrocannabiorcol (Δ9-THCO-C1)
  12. Delta-9-Tetrahydrocannabiorcolic acid A (THCOA)
  13. Delta-9-tetrahydrocannabivarin (THCV)
  14. Delta-9-tetrahydrocannabivarinic acid A (THCVA)
  15. TriHydroxy-delta-9-tetrahydrocannabinol (TRIOH-THC)
  16. Delta-10-tetrahydrocannabinol (D10THC, Δ10THC)
  17. Tetrahydrocannabiphorol (THCP)
  18. THC-O Acetate (THCO)
  19. Hexahydrocannabinol (HHC)

In regards to all the different types of THC we just shared, we can break these down into two main categories, THC Analogs, which are naturally-derived from cannabis plant material, and THC Derivatives, which are man-interfered.

THC Analogs

THC’s complexity lies in its many varieties. All these alternatives, or analogs, have a similar molecular structure with one major difference – the placement of atomic double bonds. This subtle alteration is enough to create vastly different effects when used by consumers!

THC Derivatives

The definition of a derivative cannabinoid, which I will paraphrase according to Utah’s state legislature.

Derivative cannabinoids are chemical compounds, enabled through man-made processes that use existing cannabinoid compounds to create new compounds. 

With each derivative, the atomic structure changes, and if the derivative can associate with the ECS (later discussed in this article) it could offer a unique potential for medical and therapeutic applications.

The Strongest Types Of THC

We’ve listed the THC-types from strongest to weakest in regards to potency

  1. THCP (Strongest/Most Potent)
  2. THC-O
  3. Delta 9
  4. HHC
  5. Delta 8
  6. Delta 10
  7. THCV (Least Potent)

How Different THC Molecules Get Their Specific Numbers

Did you wonder why THC has numbers associated with it?  A lot of people might not pay attention to this subtle common characteristic but in regards to THC, it’s kind of important or at least, very cool to know

To find out how the different types of THC obtain their number, we have to go to the atomic level and look at the carbon molecules, specifically.

THC has an important double bond associated with its molecules and based on where this double bond is located, is how each THC-type received their number.  I.e.

  • Δ8-THC has a double bond on the 8th carbon
  • Δ9-THC has a double bond on the 9th carbon
  • Δ10-THC has a double bond on the 10th carbon

 

See? I told you its kind of cool.

The History Of THC

The use of marijuana dates back thousands of years and has been used both medicinally and ceremonially by many cultures around the world.

  • The first recorded use was by the Chinese Emperor Shen Nung in 2737 BC as a treatment for gout, rheumatism, malaria, constipation, menstrual disorders and memory loss.
  • Since then, marijuana has been widely used throughout Asia, Africa and Europe as a medicinal herb until it was outlawed in 1937 with the passing of the Marihuana Tax Act in the United States.
  • In 1964 that its chemical structure was identified by Israeli scientist Raphael Mechoulam at Hebrew University in Jerusalem.
  • It wasn’t until 1996 that California became the first state to legalize medical marijuana for patients suffering from serious illnesses such as cancer or AIDS.
  • Today there are more than 30 states that have legalized the use of medical marijuana for certain conditions of chronic health issues such as glaucoma or multiple sclerosis.
  • Recreational marijuana use is also legal in 11 states plus Washington D.C., although its sale is still prohibited under federal law. With public opinion shifting towards legalization across many parts of the U.S., one can expect more states to follow suit soon enough!

How THC Interacts With The Body

It binds to receptors in the brain and can produce feelings of euphoria, relaxation, altered perceptions of time and space, as well as increased appetite.

THC also has some purported medicinal and therapeutic benefits such as reducing nausea and improving pain relief for certain conditions (source).

Another way THC works in the human body as well as the majority of all living creatures is by interacting, influencing, and/or supporting the ECS.

Endocannabinoid System

Endocannabinoid System, AKA ECS, is broken up into the following three categories:

  1. Endocannabinoids
  2. Cannabinoid receptors
  3. Metabolic Enzymes

To learn more about the Endocannabinoid System, click here.

THC Benefits: The Possible & The Approved Medicinal & Therapeutic Applications

First and foremost, any information shared here ARE NOT MEDICAL CLAIMS, I am just reporting on the information that is publicly available.

Furthermore, as I share information in this section, please note that I am cover Delta 9 THC, specifically.  The reason for this is because each type of THC offers its own unique properties.  Their individual atomic structures results in very  specific ways on how each type of THC interacts with the body when consumed. 

For example, Δ9-THC is very psychotropic, but it’s reported that THCP seems to have 30x stronger psychoactive and psychotropic effects compared to Delta 9. While THCV has little psychotropic effects and also seems to act as an appetite suppressant or stimulant depending on dosage.

As you can see, these are all THC molecules, but each with their own effects and benefits. Long story short and for sincere clarity, any “THC benefit” or potential “medicinal/therapeutic application” listed in this section should be automatically insinuated as a Delta-9 THC reference.

Approved THC Products For Medicinal Uses & Treatments

  • Epidiolex
  • Marinol and Syndros, which contain dronabinol (synthetic THC)
  • Cesamet, which contains nabilone (a synthetic substance similar…

The terpenes in cannabis.

Check out this Systematic review from the British Journal of Pharmacology. They mention all of the following but much more explicit in detail:

  • nausea and/or vomiting
  • Dealing with low appetite
  • dronabinol (look up study)
  • epilepsy
  • chronic pain
  • anxiety
  • sleep
  • dry mouth
  • red eyes
  • increased heart rate
  • overall mental health

If this information interests you, please continue learning our article on The Benefits Of THC Gummies.

Benefits of CBD & THC Combined

When combining CBD products with THC products, studies show that it may be beneficials in the management of symptoms of chronic pain relief.

You see the potential benefits, but are there effects of marijuana on the human body and brain?

The Risks & Side Effects of Cannabis

Historically, the use and consumption of Cannabis, which goes hand in hand with the consumption of THC for both recreational use and medical use has been connected to several risks and adverse health effects that you should know about.

  • schizophrenia
  • psychosis
  • impairment
 

The long term negative effects are horrible, but are there serious short-term adverse effects?

We offer a deep dive into the side effects of THC gummies which covers both the short-term and long-term effects of THC.  With that said, a topic we must address here is THC overdoing possibilities/THC intoxication.

Cannabis Overdose & THC Intoxication

After ingestion, its important to weight 2-3 before your next edible because as THIS DOCTOR SAID, the second dose gets taken too soon and now the consumer unknowingly took an unneeded double dose.

The Notable Differences Between Delta 8 THC & Delta 9 THC

There are a few things that make these two differ from each other so lets take a look at each one.

  1. The psychotropics effects of D8 THC compared to its more potent counterparty D9 THC is that delta-8 THC boasts a subtler high experience ranging 2-3 times milder.
  2. At the atomic level, Delta 8 THC has a double bond found at the 8th carbon instead of 9th carbon like Delta 9 THC.
  3. Delta-8 THC has earned the nicknames ‘diet weed‘ and ‘marijuana lite‘, due to its scientifically backed difference in potency compared to Delta-9.
  4. Delta 8 THC molecules have a lower affinity to CB1 receptors in comparison to Delta 9 THC molecules.
  5. There is less D8 available than D9 at the time of harvesting a cannabis plant. Specifically depending on the cultivar, the average potency of delta 8 is less than 1% and delta 9 THC being somewhere around 15%.
  6. Delta 8 THC molecules are only NATURALLY available by the degradation of Delta 9 THC molecules.  Without Delta 9, Delta 8 would not exist.

Popular THC Timeframes

Here are three important topics that we’ve dedicated individual articles to that we recommend reading. If you’re interested in learning the THC timeframes of specific questions that we get all the time, below I’ll introduce each one and offer a link for your convenience.

How Long It Takes For THC Effects To Kick In

You’re about to partake in a brand new experience with one of the latest THC products on the market for the first time. It could be a THC tincture, THC Beverage, THC capsule, Marijuana Strain (proper term = cultivar), or our personal favorite, a THC gummy, and now you want to know the onset time of when euphoria is supposed to kick in.  If you find yourself in this category, we recommend the following for a clear look at How Long Do Edibles Take To Start Working?

How Long The Effects Of THC (High) Will Last

Perhaps you are planning on taking a THC gummy, brownie, or any other edible for the first time or maybe you’re already super stoned and you are worried about how long the high will last, either way, this article is for you –  How Long Do The Effects Of Edibles Last?

How Long THC Will Stay In Your System

As the THC product industry continues its growth, more and more consumers are worried about failing their job-required, THC-triggered drug tests, or for any other particular reason.  If this is one of your concerns or if you simply want to know how long Tetrayhydrocannabinol will be detectable after taking a THC edible product whether it be via urine, hair, or sweat test, please read How Long Do THC Edibles Stay In Your System?

Conclusion

Tetrahydrocannabinol (THC) is one of the most popular compounds found in cannabis plants due to its intoxicating effects when consumed or applied topically through products like oils or balms.

There are several different types of THC products infused with specific cannabinoid analogs and derivatives that are available online; each having their own unique properties. For example:

  • Δ8-THC gummies
  • Δ9-THC gummies produce both psychoactive and psychotropic effects.
  • THC-O gummies
  • CBD gummies don’t produce any psychogenic effects, but they seem to provide a host of potential medicinal benefits
  • CBN gummies don’t offer any type of high, but they’re purported to aid with people having trouble with sleeping.

You see, with the right knowledge about phytocannabinoids, and for this article, THC specifically, you can make an informed decision about which THC product would be best suited for your needs; whether it be recreational or medical in YOUR OPINION.

Ultimately though, all forms should be approached with caution since they all have potential risks associated with them due to their varying levels of potency, age on the market, or lack of authoritative research on the specific THC-type of product in question. 

Speak to a medical professional before considering to add THC to your diet and as always, ENJOY RESPONSIBLY!

References

All informational sources and references were citied throughout the article, any additional sources not cited can be found below:

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