* These Cannabis Gummies are for health & wellness purposes, not recreational.
The House of “Noids”
This segment of our blog probes the infamous and famous cannabinoids we all know and love (and a few I’m sure you’ve never heard of). This is your go-to hub for all things cannabinoid-related.
We’ll cover Phytocannabinoids within cannabis plants and their intricate hierarchy. We’ll open the doors to man-made Synthetic and Semi-synthetic cannabinoid compounds. Then, we’ll illuminate more on the exciting details of the Endocannabinoids within our bodies.
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Cannabinoids are a remarkable family of chemical compounds that have a special way of interacting with certain spots, known as cannabinoid receptors, in the cells of our body.
They are like the special guests that trigger a celebration, altering the release of neurotransmitter party-goers (chemical messengers) in the brain’s grand hall.
These receptors are part of the larger, bustling community known as the endocannabinoid system, playing a crucial role in everyday happenings of our bodily neighborhood, influencing things like our appetite, how we feel pain, our mood swings, and how we store memories.
To date, researchers have identified 180 distinct cannabinoids, each purported to deliver unique effects to the user. Evidence increasingly suggests that cannabinoids hold recreational, medicinal, and therapeutic potential.
Here’s a glimpse into the variety within the cannabinoid realm:
These are cannabinoids produced naturally within the body, like anandamide and 2-AG, playing a key role in the internal harmony and regulation of body processes. Imagine your body as a cozy home where endocannabinoids are the hosts, ensuring everything is in order, making you feel comfortable and balanced.
Originating from plants, particularly the cannabis plant, these include well-known compounds like THC and CBD which mimic the action of endocannabinoids by interacting with the body's cannabinoid receptors. Picture a friendly neighbor (the cannabis plant) lending you some sugar (phytocannabinoids) that surprisingly fits perfectly in your coffee, adding the sweet balance just like your own sugar would.
Created in the lab, these compounds are designed to mimic the effects of natural cannabinoids, often with stronger or more predictable effects, used in research and sometimes in medical settings. Picture scientists crafting a key from scratch that can unlock a special door within your body, leading to new discoveries on how to keep us feeling good.
These are derived by making modifications to the phytocannabinoids, aiming to enhance their therapeutic effects or reduce side effects. Imagine taking that sugar from your neighbor, refining it a bit in your kitchen to suit your taste even better - that’s what happens with semi-synthetic cannabinoids, they are tweaked to perfection in a lab.
Each of these members from the cannabinoid family has a unique tale to tell, showcasing the harmonious blend of nature, science, and our body’s own ingenuity.
The world of cannabinoids is indeed a blend of the familiar and the extraordinary, opening doors to understanding our body better and finding new paths to wellness.
View the following article for a DEEP DIVE into the differences between each type of cannabinoid.
The classification of major and minor cannabinoids primarily hinges on their abundance in the cannabis plant and the extent of their researched effects on the human body.Â
Here’s a more nuanced breakdown based on our gathered information:
The major cannabinoids below, especially THC and CBD, have been extensively researched due to their prevalence and notable effects. Here are quick descriptions of the following cannabinoid-specific articles you can learn more about if you wish more information on:
Minor cannabinoids are usually present in lower concentrations in the cannabis plant. Here’s a brief intro for each:
There is a lot of debate on whether or not CBD is “psychoactive,” we bring you the facts in the following article.
The top two phytocannabinoids in the history of mankind go head to head in this comparative article; a cannabinoid battle for glory, honor, and respect!
If you really want to understand these magical hemp and marijuana compounds, you should learn more about these terms!
Oxidation:
A chemical reaction in which a substance loses electrons, often resulting in the addition of oxygen to a molecule or the removal of hydrogen.
Oxidative Degradation:
The breakdown of organic compounds due to reactions with oxygen.
Isomerization:
A chemical process by which a compound is transformed into any of its isomeric forms, i.e., forms with the same molecular formula but different structural arrangements.
Metabolic Byproduct:
A secondary or incidental product resulting from the metabolism of a primary compound.
Synthase:
An enzyme that catalyzes the synthesis of a specific compound or compounds in biological systems.
Decarboxylation:
The process of applying heat to convert cannabinoids in their acid form to their active form. For instance, turning THCA into THC.
Entourage Effect:
The theory that all the compounds in cannabis work together, and when taken together, they produce a better effect than when taken alone.
Flavonoid:
A group of phytonutrients responsible for the vivid colors in fruits, vegetables, and flowers, also found in cannabis. Some have medicinal properties.
Anandamide:
Commonly referred to as “The Bliss Molecule,” anandamide is an endocannabinoid, also known as N-arachidonoylethanolamine (AEA), which plays a role in pain, depression, appetite, memory, and fertility.
Derivative:
A compound that originates from a parent compound by the replacement of one or more atoms or groups or by other types of chemical transformations.
Homolog:
In organic chemistry, homologs are compounds in a series that have the same general formula but differ by a constant unit, often CHâ‚‚.
These cannabinoids are naturally found in marijuana and hemp plants, but are not abundant enough for commercial purposes. This lack has led to innovative molecule manipulation techniques that make these less-available cannabinoids more accessible for product infusion.
In the intricate world of cannabinoids, their diversity is not just confined to their origins like plants or the human body, but extends to their molecular structures and stages of development.
Broadly, cannabinoids can be categorized into three distinct groups:
Each group showcases a unique facet of cannabinoid chemistry and functionality, often organized as the hierarchy of cannabinoids.
CBGA (Cannabigerolic Acid)
CBDA (Cannabidiolic Acid)
THCA (Tetrahydrocannabinolic Acid)
CBCA (Cannabichromenic Acid)
CBDVA (Cannabidivarinic Acid)
THCVA (Tetrahydrocannabivarinic Acid)
CBCVA (Cannabichromevarinic Acid)
CBGVA (Cannabigerovarinic Acid)
CBG (Cannabigerol)
CBD (Cannabidiol)
THC (Tetrahydrocannabinol)
CBC (Cannabichromene)
CBL (Cannabicyclol)
CBDV (Cannabidivarin)
THCV (Tetrahydrocannabivarin)
CBCV (Cannabichromevarin)
CBGV (Cannabigerivarin)
CBN (Cannabinol)
Variants of THC:
Δ9-THC
Δ8-THC
Δ10-THC
Variants of CBG:
Δ9-CBG
Δ8-CBG
Variants of CBC:
Δ9-CBC
Δ10-CBC
Variants of CBD:
Δ9-CBD
Variants of THCV:
Δ9-THCV
Variants of CBGV:
Δ9-CBGV
Variants of CBN:
Δ9-CBN
In conclusion, the multifaceted nature of cannabinoids, encapsulated in the acidic forms, neutral cannabinoids, and the various cannabinoid variants, unfolds a complex yet enthralling narrative.
This narrative not only deepens our understanding of the cannabis plant but also broadens the horizon for medical research and therapeutic applications.
The transformation from acidic precursors to neutral cannabinoids, along with the broad spectrum of cannabinoid variants, underscores the intricate interplay of chemistry, biology, and human health in the evolving story of cannabis and cannabinoid science.
Cannabinoids are diverse chemical compounds with major categories including endocannabinoids produced naturally within the body, phytocannabinoids originating from plants like cannabis, and synthetic/semi-synthetic cannabinoids crafted or modified in laboratories.
Cannabinoids interact with cannabinoid receptors in our bodies, playing pivotal roles in physiological processes like mood, appetite, and pain sensation.
Our exploration today has unraveled a complex and captivating narrative of the cannabinoid realm, each category contributing to a broader understanding of their potential benefits and applications in wellness and medicine.
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